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#AAN2018- Inbrija Reduces Parkinson’s Off Periods, Phase 3 Trial Shows. Inbrija reduces Parkinson’s symptoms when standard treatments wear off, and decreases the length of these off periods, a Phase 3 clinical trial shows. The therapy’s developer, Acorda Therapeutics, will present the results at the American Academy of Neurology annual meeting in Los Angeles, April 21-27. Parkinson’s News Today will be covering the conference. Another finding was that patients were able to regain control of their symptoms within 60 minutes. The U.S. Food and Drug Administration accepted Acorda’s New Drug Application for Inbrija in February 2018. It is expected to decide whether to approve it by October 5. ParkinsonsNews.

Parkinson's disease symptoms tend to get worse over time, and there are a number of warning signs for the brain condition. These are five symptoms of Parkinson’s, including the three major signs. 1. One of the most noticeable signs of Parkinson's is a tremor that often starts in the hands or fingers when they are relaxed. 2, Slowed movement - Parkinson's can slow your movement making simple tasks more time-consuming. It may become difficult to walk or get out of a chair. 3, Slowed movement - Parkinson's can slow your movement making simple tasks more time-consuming. It may become difficult to walk or get out of a chair. 4, Loss of balance - some sufferers will notice balance problems. 5, Speech difficulties - One of the signs of Parkinson's disease can be speech problems, such as speaking softly, quickly, slurring or in a monotone. 6, Speech difficulties - One of the signs of Parkinson's disease can be speech problems, such as speaking softly, quickly, slurring or in a monotone.7, Loss of automatic movements - Unconscious movements such as smiling, blinking and swinging your arms are greatly reduced in Parkinson's sufferers. 8, Writing difficulties - A person with Parkinson's may find it hard to write and their writing may appear small. 9, Posture problems - Over time your posture may become stooped. There’s currently no cure for Parkinson’s disease, the NHS said. But, some treatments can help to relieve symptoms, and maintain quality of life. While the condition itself doesn't cause people to die, it can make patients more vulnerable to serious or life-threatening infections. Regular exercise and eating a healthy, balanced diet are crucial to staying physically and mentally healthy. About 127,000 people in the UK have Parkinson’s disease. Matt Atherton: Express.

Diet and Parkinson's Disease. Low blood pressure is common with Parkinson's, so keeping well hydrated with water and eating small, frequent meals can be beneficial. Good hydration may also help to ease cramping, another side effect associated with the condition. Eat more vegetables than fruit include as many different colours. Choose organic if possible. If you are taking medication for Parkinson's, keep in mind that protein can reduce the absorption and effectiveness of your l-dopa medication. Levodopa is a protein building block so it competes for absorption with other proteins. Some people find their medication works better if they eat carbs and vegetables around the time of their l-dopa medication and have their protein based meals at a different time. Protein foods include fish, eggs, chicken, meat, pulses (lentils/beans), nuts and seeds. Keep sugar to a minimum and avoid white and refined carbohydrates. Avoid strong stimulants such as coffee, tea and energy drinks and drink mild stimulants such as green tea only occasionally. Keep alcohol to a minimum. Support a healthy digestive system by relaxing before you eat and chewing your food thoroughly. Probiotic supplements and/or live yogurt support a healthy gut environment and may be recommended, particularly if you have digestive symptoms like constipation. Eat fish at least twice a week (mackerel, herring/kipper, sardines, anchovy, salmon and trout). Packed with omega 3 fats to help support the brain. Have a handful of nuts and seeds every day. Try milled seeds if you have digestive problems. Research shows that people with Parkinson's have lower levels of vitamin D than the rest of the population. Consider supplementing vitamin D at 2200iu a day, especially between October and May, due to lack of sunlight. The Irish News.

The Express says, that scientists have created a new brain implant that can slow down the progression of Parkinson's disease and give sufferers a fuller life. Sky News: Press Preview.

Back to the Future star Michael J Fox has pledged more than £100,000 to a UK university to develop an App that monitors symptoms of Parkinson's disease. The tool-kit will help develop clinical measures that could lead to early identification of problems such as side-effects from medications, and individualised patient profiles that help with assessment. Metro.

It has been a remarkable year of promise in medical science. The highlights. Incurable diseases from sickle cell to haemophilia now look as though they can be treated. The defect that causes the devastating degenerative disease Huntington's has been corrected in patients for the first time. BBC News.

Scientists have found the first parts of a possible chemical test for Parkinson’s thanks to the nose of a Scottish woman who can smell the disease. Joy Milne, a 67-year-old retired nurse from Perth, began to notice an increasingly musky note in the scent of her husband Les, about a decade before he was diagnosed with the condition in 1997. A subsequent experiment by researchers at the University of Edinburgh established that Mrs Milne could accurately determine which of a dozen T-shirts had been worn by Parkinson’s patients from their smell. Times.

Exercise reduces tremors, limb rigidity, slowness of movement and balance, scientists have said. The study of 128 patients found it prevented the devastating symptoms from worsening for at least six months – and the benefit could last longer.Participants who indulged in short bursts of hard physical activity were 15 per cent better off than those who remained sedentary – enough to make a difference to their quality of life. Daniel Corcos, professor of physical therapy and human movement sciences at North-western University in Chicago, said: “If you have Parkinson’s disease and you want to delay the progression of your symptoms you should exercise three times a week. It’s that simple.” Express.

New drug for Huntington's disease. There are about 10,000 cases in the country. Its one of these neural degenerate diseases. What they inherited is a single-gene defect that allows cells to make up toxic protein that attacks the brain cells that cause these symptoms which include personality changes, mood swings. Jerking and twisting of the limbs. Slurring words and and end up in nursing care. The good thing about this injection is they found out this gene called toxic protein and they've created this experimental drug which is injected into the spine of the patient once a month for four months with ever increasing doses. Its quite safe, a few side effects and they measured this toxic protein and the levels dropped dramatically. The professor said, The results are beyond what I ever hoped for. Very, very excited. Great for Huntington patients and this type of technology could be used for and alzheimer's and Parkinson's. Dr Chris Steele. ITV This Morning.

Huntington's disease is one of the most devastating diseases. Its been described as Parkinson's, alzheimer's and motor neuron disease rolled into one. Presenter Jeremy Vine: Radio 2.

November 7, 2017. Parkinson's, a disease of the central nervous system. As the system progresses, people with Parkinson's develop tremors, lose their ability to move, and their balance. They're more at risk of falling and are therefore likely to break their limbs. The average age of diagnosis is 60. In Canada 25 people a day are diagnosed with the condition which is expected to rise as the population increases.As the disease progresses, Parkinson's sufferers movements get so small, they may simply lose the ability to move. High intensity training really helps. BBC World Service Health Check.

Getting diagnosed early with almost any condition the better. With bowel cancer these days, we didn't have them back then, but we've now got this new bowel-scope screening which means we can actually prevent some cases of bowel cancer. as well as most conditions whether its Parkinson's, dementia, anything. Getting diagnosed early means we can put steps in place, getting treatment if you need to, but actually making sure if things do persist, we know exactly where we are. Dr Sarah Jarvis. Radio 2.

Asthma drug to stop Parkinson's. A drug called salbutamol is used as an inhaler in asthma. A study of 600.000 asthmatics who were using salbutamol for 11 years. They found that those users were one-third less likely to develop Parkinson's disease.  The drug dampens the activity of a gene that's implicated in Parkinson's disease. It's very early days but an interesting finding. Dr Chris Steele. ITV This Morning.

Study after study into Parkinson's has looked at its causes, and numerous potential treatments have been put forward, however, it still remains sadly incurable, but new research has offered some hope. It's been suggested that a drug, 'Exanatide', normally used for diabetes could halt the prevention of Parkinson's. Patients who took the drug during a trial at University College London did not deteriorate. Some even had a slight improvement in their symptoms. Presenter Jeremy Vine: Radio 2.

Exanatide is the name of the drug. the related proteins called Exendin-4 was first discovered in the venom saliva of the Gila monster, which is an animal that lives in the Arizona desert. There's a precedent of finding drugs that are present in animals, and it was found that this drug has an effect on the insulin release in the peripheral circulation, and can control blood sugars very accurately, so this, over the course of several trials became a licensed treatment for diabetes, and during those trials, while they were being conducted, other researches looked to see what Exanatide does to nerve cells in the laboratory, and then also to animal models that we can create that are similar to Parkinson's disease. and in all of those, we found encouraging data that it can protect nerve cells against loss. Professor Tom Falcony. National Hospital for Neurology and neurosurgery. Jeremy Vine: Radio 2.


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